Research Scientist, Karthick Lab, College of Med, Dept of Pharmacology, Physiology & Neurobiology (Cincinnati, OH, US, 45221)

University of Cincinnati
University of Cincinnati

Cincinnati, OH, USA

Posted on Oct 20, 2026

Current UC employees must apply internally via SuccessFactors

Next Lives at the University of Cincinnati

Founded in 1819, the University of Cincinnati ranks among the nation’s best urban public research universities. Home to more than 53,600 students, 12,000 faculty and staff, and over 360,000 living alumni, UC, a Carnegie 1 institution, combines research prowess with a physical setting The New York Times has called “the most ambitious campus design program in the country." UC's momentum has never been stronger as the anchor of the Cincinnati Innovation District, the oldest cooperative education (co-op) program in the country with students earning $94 million annually through paid experiences, an academic health system, and as a member of the Big 12 Conference. The university contributes $10.6 billion in economic impact to the city and $22.7 billion to the state of Ohio. At UC, next is all of us. Learn more at uc.edu.

UC is a mission-driven organization where we are committed to student success and positively transforming the community through scholarship and service. We thrive on innovation, making an impact, and fostering an environment where staff and faculty are key contributors to UC’s success.

Job Overview

As one of the oldest medical schools in the country, the UC College of Medicine has a reputation for training best-in-class health care professionals and developing cutting-edge procedures and research that improves the health and clinical care of patients.

A Research Scientist position is available in the laboratory of Dr. Karthick Chella Krishnan (www.med.uc.edu/klab) in the Department of Basic Biomedical Sciences, Division of Cardiovascular Biology, Metabolism and Pharmacology, at the University of Cincinnati College of Medicine. The K Lab conducts mechanistic research at the intersection of mitochondrial biology, metabolism, genetics, and sex differences, with projects spanning the liver, adipose tissue, heart, and hippocampus.

The laboratory focuses on understanding how genetic background and sex shape mitochondrial adaptation and dysfunction and contribute to cardiometabolic disease. Current research areas include mitochondrial subpopulations, sex-dependent metabolic regulation, genetic determinants of mitochondrial function, and organ-to-organ communication.

Essential Functions

  • Perform in-depth studies of mitochondrial function and metabolism using isolated liver mitochondria, primary or immortalized liver cells, human iPSC-derived hepatic organoids, and mouse models.
  • Elucidate the molecular mechanisms regulating mitochondrial function and metabolism in metabolic and cardiometabolic disease using a combination of biochemical, molecular, cellular, and mouse genetic approaches.
  • The goal of this research is to understand how alterations in mitochondrial function and metabolism contribute to disease pathogenesis and to identify mechanisms that may provide new insights into therapeutic approaches for the improvement of human health.

Daily tasks will include:

  • Independently designing and conducting research as required by the faculty supervisor and in accordance with all institutional and federal regulations;
  • Modifying and adapting experimental protocols (i.e., troubleshooting), techniques and procedures to address project-specific experimental challenges and requirements;
  • Supporting the development of proposals and writing research-related funding and grants;
  • Analyzing and interpreting data, preparing research results and written summaries in manuscript form for publications and in graphics form for presentation at research meetings and for grant proposals;
  • Independently writing manuscripts and engaging in the dissemination of research findings;
  • Contributing to a collaborative laboratory environment by training and mentoring student researchers in research methods and laboratory procedures;
  • Maintaining and ensuring compliance with applicable regulatory protocols, laboratory records, and institutional requirements;
  • Undergoing training in and developing proficiency with mitochondrial physiology, cellular and molecular biology techniques, metabolic phenotyping, laboratory instrumentation, and data analysis relevant to the laboratory's research projects.

Required Education

  • PhD in Biotechnology, Biochemistry, or related field.

Physical Requirements/Work Environment

  • Office environment/no specific unusual physical or environmental demands.

Compensation and Benefits

UC offers an exceptional benefits package designed to support your well-being, financial security, and work-life balance. (UC Benefits) Eligibility may vary by position and FTE status. Highlights include:

Comprehensive Tuition Remission

UC provides tuition remission for you and your eligible dependents, covering tuition costs for nearly all undergraduate and graduate programs offered by the university.

Robust Retirement Plans

As a UC employee, you won’t contribute to Social Security (except Medicare). Instead, you’ll choose between state pension plans (OPERS, STRS) or an Alternative Retirement Plan (ARP), with UC contributing 14–18% of your salary based on position.

Real Work-Life Balance

UC prioritizes work-life balance with a generous time-off policy, including:

Vacation and sick time

11 paid holidays and additional end-of-year paid time off (Winter Season Days)

6 weeks of paid parental leave for new parents

Additional Benefits Include:

  • Competitive salary based on experience
  • Comprehensive health coverage (medical, dental, vision, prescription)
  • Flexible spending accounts & wellness programs
  • Professional development & mentorship opportunities

To learn more about why UC is a great place to work, please visit our Careers Page.

UC is an E-Verify employer. If hired into this position, you will be required to provide satisfactory proof of employment eligibility by providing acceptable, original forms of identification for employment verification via the Federal I-9 employment verification process. Click here for a list of acceptable documents.

Important: To apply you must create a profile and submit a complete job application through the UC applicant portal. We are unable to consider “easy apply” applications submitted via other websites. For questions about the UC recruiting process or to request accommodations with the application, please contact UC HR at jobs@uc.edu.

Equal Opportunity Employer. Building a workplace where all qualified applicants will receive consideration for employment, including Individuals with Disabilities and Protected Veterans.

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